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Sunday, November 23, 2008
Bones, Joints, & Muscles Center
Fibromyalgia
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Causes of fibromyalgia

The cause of fibromyalgia is not known, but there are several theories. Fibromyalgia may develop following a bout of flu or other illness or after extreme physical or emotional stress. Some researchers believe that fibromyalgia results from minor, repeated trauma to the muscles that decreases blood flow to them and causes weakness and fatigue.

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Another theory is that the sleep disturbance associated with fibromyalgia is the underlying cause of the syndrome. The deepest, restorative stage of sleep--delta-wave sleep--is somehow disrupted in people with fibromyalgia.

Other researchers suggest that an abnormality in the central nervous system is responsible. One possibility is a brain malfunction in the production or metabolism of the neurotransmitter serotonin, which plays an important role in some of the fibromyalgia symptoms relating to pain, mood, and sleep. Low blood pressure is currently under investigation as another potential cause of the symptoms of fibromyalgia.

Content last updated: 5/2/06Previous PagePrevious page Next Section: SymptomsNext Page



Content excerpted from the Johns Hopkins White Paper on Arthritis.




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