Medical Trials Ignore this Placebo Effect

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UMZDcwVLxeFvmkkX of 11:30AM August 10, 2009

There are many situations where it is very hard to have a suitable placebo. For example in Nicotine Replacement trials (using gum or patches) - how can a placebo mimick the effect of the nicotine which causes a significant stimulation of the nervous system. If I remember correctly the stronger the side-effects the greater the placebo response.

Mark Davis 5:15AM June 11, 2009

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keydayirreway of AL 7:10PM April 14, 2009

The bane of trusting statistics is that almost no test population is either truly homogenious, or constant in attributes,whether you are testing lifetime of light bulbs or of people. A random coin toss recorded on checkerboard squares will usually show a 'cluster' - an area of all heads or tails that seems non-random.
The growing ability to find correlation of genetic profile with disease susceptibility strongly suggests that positive or negative effects -at the level of a few percent may often be measuring the effects of different genetics more than of response to disease. EZ

Ed Zebroski of CA 9:49PM December 28, 2007

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This blog is the public workshop of U.S. News writer and editor Ben Harder. In articles published in the magazine, he has covered a range of sciences, including medicine, human behavior, prehistory, and evolution. Here, he can explore those and other scientific fields more fully and more informally than is possible in print. He'll share whatever seems noteworthy or potentially useful, and he invites readers to do the same.

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