Scientists Turn Stem Cells Into Pork

January 15, 2010 RSS Feed Print

MARIA CHENG,
AP Medical Writer

LONDON—Call it pork in a petri dish — a technique to turn pig stem cells into strips of meat that scientists say could one day offer a green alternative to raising livestock, help alleviate world hunger, and save some pigs their bacon.

Dutch scientists have been growing pork in the laboratory since 2006, and while they admit they haven't gotten the texture quite right or even tasted the engineered meat, they say the technology promises to have widespread implications for our food supply.

"If we took the stem cells from one pig and multiplied it by a factor of a million, we would need one million fewer pigs to get the same amount of meat," said Mark Post, a biologist at Maastricht University involved in the In-vitro Meat Consortium, a network of publicly funded Dutch research institutions that is carrying out the experiments.

Post describes the texture of the meat as sort of like scallop, firm but a little squishy and moist. That's because the lab meat has less protein content than conventional meat.

Several other groups in the U.S., Scandinavia and Japan are also researching ways to make meat in the laboratory, but the Dutch project is the most advanced, said Jason Matheny, who has studied alternatives to conventional meat at the Johns Hopkins Bloomberg School of Public Health in Baltimore and is not involved in the Dutch research.

In the U.S., similar research was funded by NASA, which hoped astronauts would be able to grow their own meat in space. But after growing disappointingly thin sheets of tissue, NASA gave up and decided it would be better for its astronauts to simply eat vegetarian.

To make pork in the lab, Post and colleagues isolate stem cells from pigs' muscle cells. They then put those cells into a nutrient-based soup that helps the cells replicate to the desired number.

So far the scientists have only succeeded in creating strips of meat about 1 centimeter (a half inch) long; to make a small pork chop, Post estimates it would take about 30 days of cell replication in the lab.

There are tantalizing health possibilities in the technology.

Fish stem cells could be used to produce healthy omega 3 fatty acids, which could be mixed with the lab-produced pork instead of the usual artery-clogging fats found in livestock meat.

"You could possibly design a hamburger that prevents heart attacks instead of causing them," Matheny said.

Post said the strips they've made so far could be used as processed meat in sausages or hamburgers. Their main problem is reproducing the protein content in regular meat: In livestock meat, protein makes up about 99 percent of the product; the lab meat is only about 80 percent protein. The rest is mostly water and nucleic acids.

None of the researchers have actually eaten the lab-made meat yet, but Post said the lower protein content means it probably wouldn't taste anything like pork.

The Dutch researchers started working with pork stem cells because they had the most experience with pigs, but said the technology should be transferable to other meats, like chicken, beef and lamb.

Some experts warn lab-made meats might have potential dangers for human health.

"With any new technology, there could be subtle impacts that need to be monitored," said Emma Hockridge, policy manager at Soil Association, Britain's leading organic organization.

As with genetically modified foods, Hockridge said it might take some time to prove the new technology doesn't harm humans. She also said organic farming relies on crop and livestock rotation, and that taking animals out of the equation could damage the ecosystem.

Some experts doubted lab-produced meat could ever match the taste of real meat.

"What meat tastes like depends not just on the genetics, but what you feed the animals at particular times," said Peter Ellis, a biochemistry expert at King's College London. "Part of our enjoyment of eating meat depends on the very complicated muscle and fat structure...whether that can be replicated is still a question."

If it proves possible, experts say growing meat in laboratories instead of raising animals on farmland would do wonders for the environment.

Tags:
stem cells,
science

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