Rothman and Schekman won the Albert Lasker Basic Medical Research Award for their research in 2002 — an award often seen as a precursor of a Nobel Prize. Sudhof won a Lasker last month.
Established by Swedish industrialist Alfred Nobel, the Nobel Prizes have been handed out since 1901.
Last year's Nobel in medicine went to Britain's John Gurdon and Japan's Shinya Yamanaka for their contributions to stem cell science.
Karl Ritter reported from Stockholm. Associated Press writers Malin Rising in Stockholm, Frank Jordans in Berlin, Matt Surman in London, and Stephen Singer in Hartford, Conn. contributed to this report.
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