Not all his material worked. One bit that fell flat had Kimmel's parents, or so the host said, escorted out of the theater because they promised he would win an Emmy and he didn't.
"Family Guy" creator Seth MacFarlane found presenting can be tricky.
"Oh, the mic's over there," he said, after discovering he was on the wrong side of the stage. "This is what happens when you don't come to rehearsal," MacFarlane said.
Fashionistas noticed yellow was hot, the color of choice for Moore, Danes, Bowen and Hannah Simone from "New Girl."
"Best hair and makeup goes to Danes. Perfect!" tweeted Emma Roberts.
Emmy has to prove herself a winner with the audience. After rebounding somewhat to 13.5 million viewers in 2010 after an all-time low in 2008 of 12.3 million, last year's show drew 12.4 million viewers airing on Fox. The ceremony rotates annually among the four major networks.
Television Writer Frazier Moore in New York and AP Writer Beth Harris in Los Angeles contributed to this report.