Portions of Interstate 10, the main east-west highway across northern Florida, were shut down because of flooding and remained closed late Tuesday.
In Apalachicola, the hugely popular Boss Oyster restaurant was closed for the third day in a row after the rain overwhelmed the sewers and knocked out drinking water.
"We've taken a hit," said manager Matthew Bouzemann, adding that normally up to 800 customers a day would be coming in for the oysters.
In the Panama City Beach area, there was no exodus of tourists, said Jennifer Jenkins, executive director for the Gulf County tourism council. But it wasn't business as usual.
"I think most people went to the grocery store, maybe bought some board games and just decided to hang out till it's over," she said.
Associated Press writers Tamara Lush in New Port Richey, Tony Winton in Miami, Melissa Nelson in Pensacola and Ken Thomas aboard Air Force One contributed to this report.
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