Pierce eventually left the game with a concussion, as did wide receiver Torrey Smith, who hit his head after attempting to make a leaping catch near the sideline in the third quarter.
Denver pulled away with two third-quarter touchdowns. Manning threw a 51-yard scoring pass to Eric Decker, and after the Ravens went three-and-out, Knowshon Moreno ended a 39-yard drive with a 6-yard run to make it 31-3.
Decker caught eight passes for 133 yards and Moreno finished with 118 yards rushing on 22 carries.
NOTES: Rice passed 1,000 yards rushing for a fourth straight season. ... Terrell Suggs returned for Baltimore after missing one game with a torn biceps and made one tackle. ... Hester's score was the second rushing touchdown of his career and the first since his rookie season in 2008. ... Pitta had seven catches for 125 yards.
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