The school's football program is a win away from earning a BCS berth. Charlie Strong's Cardinals travel to Rutgers on Thursday night for a game in which they could clinch the Big East's BCS bid.
The ACC's decision to add Louisville is a blow for Connecticut, which had been looking for a landing spot since Pittsburgh and Syracuse announced their Big East exits. UConn President Susan Herbst had indicated that an invitation to join that ACC is something the school would welcome.
"We will be athletically successful, regardless of our conference, because of our successes in NCAA competition," Herbst said in a statement. "... I realize this is a difficult day, but when we focus on research, discovery, and student success, we'll never go wrong."
AP Sports Writer Joedy McCreary in Raleigh, N.C., contributed to this report.