Republicans appear divided on the results.
Republican strategist Greg Mueller, who works on many conservative causes, said that if the law is upheld, the conservative base will be energized; if the law is declared unconstitutional, it will display Obama's overreach.
"I don't think there is a bad scenario for Republican candidates," he said.
Not all see it that way.
Republican Rep. Steve King of Iowa said this past week an Obama victory would be more assured if the court strikes down the individual mandate, as King would like.
"I think then that there is more risk that President Obama will be re-elected because people will think they are protected from this egregious reach into our freedom," King said.
"If the Supreme Court finds it constitutional," he added, "then I believe Barack Obama will not be re-elected because they will understand that they have to vote him out of office to repeal it."
The public's broad respect for the Supreme Court as an institution is also a factor.
"I think a wide swath of the people will say 'if the court says it's kosher, then it's kosher.' I think in many ways that will be the final word," said John Feehery, a former top Republican House leadership aide. "That doesn't mean the controversy is going to go away because this law is so massive and has so many parts that haven't been implemented yet, including the individual mandate."
The court's decision could affect the Republican presidential contest, too.
A court opinion in June would come at the tail end of the GOP primaries and ahead of the Republican National Convention.
Former Sen. Rick Santorum of Pennsylvania has elevated the health care law to his top campaign issue. He argues he would be best equipped to carry the repeal banner. Front-runner, Mitt Romney, as governor of Massachusetts, signed into law a health overhaul similar to Obama's, with an insurance requirement as part of it.
Romney has said he would seek to repeal the federal health care law, but has stood behind Massachusetts'. He argues these decisions should be left to states.
"Well, that's pretty compelling," Santorum countered sarcastically Wednesday at a rally near the shores of Louisiana's Lake Pontchartrain.
"Why would conservatives, Republicans, take the biggest issue in this race — freedom, and its impact on the economy, on your life, on your economic well-being, on your religious liberty — why would we take that issue and turn it around and give it to Barack Obama instead of using it like a sledge hammer?" he asked.
It's a case that Santorum pledges to take all the way to the floor of the convention, if he somehow manages to accomplish his long-shot goal of denying Romney enough delegates to win the nomination outright.
Health care law: http://www.whitehouse.gov/healthreform
Supreme Court: http://www.supremecourt.gov/docket/PPAACA.aspx
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