It also gave her perhaps her most memorable hit: a searing, stunning rendition of Dolly Parton's "I Will Always Love You," which sat atop the charts for weeks. It was Grammy's record of the year and best female pop vocal, and the "Bodyguard" soundtrack was named album of the year.
She returned to the big screen in 1995-96 with "Waiting to Exhale" and "The Preacher's Wife." Both spawned soundtrack albums, and another hit studio album, "My Love Is Your Love," in 1998, brought her a Grammy for best female R&B vocal for the cut "It's Not Right But It's Okay."
But during these career and personal highs, Houston was using drugs. In an interview with Oprah Winfrey in 2009, she said by the time "The Preacher's Wife" was released, "(doing drugs) was an everyday thing. ... I would do my work, but after I did my work, for a whole year or two, it was every day. ... I wasn't happy by that point in time. I was losing myself."
In the interview, Houston blamed her rocky marriage to Brown, which included a charge of domestic abuse against Brown in 1993. They divorced in 2007.
Houston would go to rehab twice before she would declare herself drug-free to Winfrey in 2009. But in the interim, there were missed concert dates, a stop at an airport due to drugs, and public meltdowns.
She was so startlingly thin during a 2001 Michael Jackson tribute concert that rumors spread she had died the next day. Her crude behavior and jittery appearance on Brown's reality show, "Being Bobby Brown," was an example of her sad decline. Her Sawyer interview, where she declared "crack is whack," was often parodied. She dropped out of the spotlight for a few years.
Houston staged what seemed to be a successful comeback with the 2009 album "I Look To You." The album debuted on the top of the charts, and would eventually go platinum.
Things soon fell apart. A concert to promote the album on "Good Morning America" went awry as Houston's voice sounded ragged and off-key. She blamed an interview with Winfrey for straining her voice.
A world tour launched overseas, however, only confirmed suspicions that Houston had lost her treasured gift, as she failed to hit notes and left many fans unimpressed; some walked out. Canceled concert dates raised speculation that she may have been abusing drugs, but she denied those claims and said she was in great shape, blaming illness for cancellations.
Houston was to make her return to film in the remake of the classic movie "Sparkle." Filming on the movie, which stars former "American Idol" winner Jordin Sparks, recently wrapped. Houston was one of the producers, and it tells the story of a family of singers ravaged by drug abuse — a story Houston knew all too well.
Associated Press writers Andrew Dalton in Los Angeles, Adrian Sainz in Memphis, Tenn., and Bruce Shipkowski in Newark, N.J., contributed to this report.
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