Liz Cheney, the daughter of former Vice President Dick Cheney, announced Tuesday that she will challenge three-term Sen. Mike Enzi, R-Wyo., for his seat next year.
Cheney will also face Thomas Bleming, an ex-mercenary, in the GOP primary. If she prevails she will join a significant list of vice presidential children who were also elected to public office.
Beau Biden, son of Vice President Joe Biden, was elected attorney general of Delaware in 2006, during his father's sixth term in the U.S. Senate.
Ben Quayle, son of former Vice President Dan Quayle, was elected to the House of Representatives in 2010. Quayle, initially seen as having a bright political future, lost his seat in Arizona two years later.
George W. Bush, son of former Vice President George H.W. Bush, was elected governor of Texas in 1994, after his father succeeded Ronald Reagan as president in 1989. He was twice elected president himself, in 2000 and 2004.
Ted Mondale and Skip Humphrey, sons of Vice Presidents Walter Mondale and Hubert Humphrey, both Democrats, made Minnesota politics a family job - or hobby, at least. The younger Mondale served as a state senator in the 1990s and Humphrey served nearly two decades as the state's attorney general, from 1983 to 1999. The two second sons faced off in a contest for the Democratic gubernatorial nomination in 1998; Humphrey won the primary, but came in third in the general election behind independent Gov. Jesse Ventura and Republican candidate Norm Coleman.