President Barack Obama's trip to Nothern Ireland and Germany will include top level talks about Syria, the global economy and trade as he meets with world leaders during the G8 summit.
He's been scheduled to have meetings with British Prime Minister David Cameron and Russian President Vladimir Putin Tuesday, his first full day.
Obama and Putin will discuss the United States' recent decision to provide Syrian rebels with light weapons and additional support, as Russia is one of the leading country's objecting to an increased United Nations role in the region.
"It's in Russia's interest to join us in applying pressure on Bashar al-Assad to come to the table in a way that relinquishes his power and his standing in Syria, because we don't see any scenario in which he restores his legitimacy to lead the country," said Ben Rhodes, White House deputy national security adviser, according to National Public Radio.
The Syrian conflict will also be discussed during a "leaders only" working dinner Tuesday, Rhodes said. Britain and France are particularly encouraged by the United States' elevated role.
"They have shared our positions generally on Syria," he said. "They've been part of the core group of 11 countries in the Middle East and in Europe that have worked together to strengthen the Syrian opposition."
Earlier in the day, Obama met with European Union leaders to discuss the Transatlantic Trade and Investment Partnership, a deal meant to open up trade.
Obama is also scheduled to deliver a speech on the east side of the Brandenburg Gate, commemorating the 50th anniversary of John F. Kennedy's famous declaration of support for Berliners.
Michelle Obama and the couple's two daughters, Sasha and Malia, are joining the president in Europe.