Dave Damore, a political science professor at the University of Nevada—Las Vegas, says Heller has also tried to reach out to the Hispanic community without abandoning his position on immigration issues that remain unpopular with those voters.
"The other problem for Heller is the vast majority of Latinos are in southern Nevada where Berkley has represented these people in Congress for a decade, where she is largely going to try and put him in a box on his positions on Hispanic issues," Damore says.
On the flip side, Duffy says Berkley needs to find a way to appeal to voters outside Las Vegas in order to win the statewide vote.
But as with the other races, the presidential race is expected to play a role in the outcome.
"The polls are within the margin of error but I just think because of the top of the ticket – Romney is just going to be a weaker candidate than Obama is – and the bottom line is that Republicans just don't have enough organization here," Damore says. "And the electorate has changed so much in just the last four years, not in favor of the Republicans."
While there are many races to watch heading into the fall, many trying to read the political tea leaves are keeping their eyes focused on the Southwest.
"If the Democrats lose New Mexico, I don't necessarily see a path for them to win the Senate, Nevada may be the difference between 50-50 or 51-49, and if the Democrats are winning Arizona that probably means they are keeping the Senate," Kondik says.
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Corrected on : Corrected on 4/09/2012: A previous version of this story stated Rep. Heather Wilson is a member of Congress. She left office in 2009.