Fat-Derived Stem Cells Might Treat MS

Small study suggests they inhibit runaway immune system response

Posted: April 26, 2009

SUNDAY, April 26 (HealthDay News) -- Stem cells taken from the fat tissue of people with multiple sclerosis (MS) may help treat the disease, suggests a preliminary study that included three patients.

The successful use of the stromal vascular fraction (SVF) cells in these patients shows that further clinical studies should be conducted into the use of SVF cells to treat multiple sclerosis and other autoimmune diseases, the researchers said.

"All three patients in our study showed dramatic improvement in their condition after the course of SVF therapy. While obviously no conclusions in terms of therapeutic efficacy can be drawn from these reports, this first clinical use of fat stem cells for treatment of MS supports further investigation into this very simple and easily-implementable treatment methodology," Dr. Boris Minev, division of neurosurgery at the University of California, San Diego, said in a news release.

In people with MS, the immune system attacks and destroys the myelin sheath that surrounds and protects nerves cells. It's believed that SVF cells, and other stem cells, may limit this immune reaction and promote the growth of new myelin.

"None of the presently available MS treatments selectively inhibit the immune attack against the nervous system, nor do they stimulate regeneration of previously damaged tissue. We've shown that SVF cells may fill this therapeutic gap," Minev said.

The study was published in the Journal of Translational Medicine.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about MS.

Stem Cell Therapy

I am on a list for a study with stem cells at the Cleveland Clinic in Ohio. I was diagnosed in 94 with M.S. and it is slowly getting worse.

Robert Daniels of MS @ Jan 28, 2010 18:33:46 PM

David Hiteshue

I've had MS for going on 17 yrs. I'm currently dealing with the worst relapse since I've found out I had MS. Can anyone point me in the right direction of a stem cell study being done nearby PA?

David Hiteshue of PA @ Jan 09, 2010 12:53:18 PM

Stem Cell Treatment for MS

I am very interested in this treatment for MS. I would like to volunteer to participate. I live in Ohio.

Pamela of OH @ Oct 18, 2009 12:01:18 PM

Add Your Thoughts
About You

advertisement

U.S. News Rankings & Research

Best Hospitals

See the best hospitals, and the best children's hospitals, in specialties from cancer to urology.

Best Health Plans

U.S. News and NCQA review over 700 health insurance plans in the Best Health Plan rankings.

Best Nursing Homes

The Best Nursing Homes rankings feature data on 15,000-plus homes. Search for one near you.

Diseases & Conditions

Get information on preventing, treating, and managing diseases and conditions. Centers:

advertisement

Sponsored Poll

What factor do you think is responsible for the majority of teen-driving crashes?

View Results

advertisement

Subscribe

U.S. News Digital Weekly

A weekly insider's guide to politics and policy — in a multimedia, digital format. 52 issues for $19.95!

U.S. News & World Report

6 months of U.S. News & World Report's print edition for only $15. Save up to 67% off the cover price!